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Hypoxic hypoxia occurs when the PO2 in the lungs is reduced, so less oxygen diffuses into the blood. This lowers arterial PO2 and hemoglobin saturation, causing a decrease in arterial oxygen content and, consequently, insufficient oxygen delivery to tissues. This situation is typical with low inspired oxygen or impaired alveolar gas exchange, such as at high altitude or with hypoventilation. The other types involve problems with oxygen carrying capacity (hypemic), oxygen transport despite normal arterial oxygen (stagnant), or cellular inability to use oxygen (histotoxic), which is why the reduction in alveolar PO2 points to hypoxic hypoxia as the correct explanation.